Multiple BCL2 mutations cooccurring with Gly101Val emerge in chronic lymphocytic leukemia progression on venetoclax

P Blombery; ER Thompson; T Nguyen; RW Birkinshaw; JN Gong; X Chen; M McBean; R Thijssen; T Conway; MA Anderson; JF Seymour; DA Westerman; PE Czabotar; DCS Huang; AW Roberts

Journal article

Multiple BCL2 mutations cooccurring with Gly101Val emerge in chronic lymphocytic leukemia progression on venetoclax

P Blombery, ER Thompson, T Nguyen, RW Birkinshaw, JN Gong, X Chen, M McBean, R Thijssen, T Conway, MA Anderson, JF Seymour, DA Westerman, PE Czabotar, DCS Huang, AW Roberts

Blood | Published : 2020

DOI: 10.1182/BLOOD.2019004205

Abstract

There is a Blood Commentary on this article in this issue.

University of Melbourne Researchers

Piers Blombery Author

Ella Thompson Author

Richard Birkinshaw Author

Mary Ann Anderson Author

Related Projects (1)

TRANSLATING ADVANCES IN MOLECULAR ONCOLOGY INTO IMPROVED CARE FOR PATIENTS WITH HAEMATOLOGICAL MALIGNANCIES

The purpose of my research is to develop and integrate into routine practice better treatment paradigms for patients with blood cancers – le..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This research was supported by grants from the Snowdome Foundation (P.B. and M.A.A.), Vision Super and the Wilson Centre for Lymphoma Genomics (P.B. and D.A.W.), the Leukemia and Lymphoma Society (fellowship 5467-18 [R.T.], SCOR 7015-18 [D.C.S.H. and A.W.R.]), the National Health and Medical Research Council of Australia (fellowships 1079700 [P.E.C.], 1043149 [D.C.S.H], and 1079560 [A.W.R.]), and grants to project 1141874 (P.E.C.), program 1113133 (D.C.S.H.), and program 1113577 (A.W.R.). This work was made possible through Victorian State Government Operational Infrastructure Support and Australian Government National Health and Medical Research Council Independent Research Institute Infrastructure Support Scheme.